Collaborative Ankle Support Trial (CAST)
This trial is now closed.
This randomised controlled trial assessed 584 patients with severe ankle sprain from eight emergency departments across the UK. Patients were provided with a mechanical support within the first 3 days of attendance by a trained health-care professional, and given advice on reducing swelling and pain. Functional outcome was measured over 9 months. The primary outcome was quality of ankle function at 3 months.
It was found that patients who received the below-knee cast had a more rapid recovery than those given the tubular compression bandage. Clinically important benefits were noted at 3 months in quality of ankle function with the below-knee cast compared with the bandage (mean difference 9%) as well as in pain, symptoms and activity.
The trial was led by Professor Sallie Lamb at the University of Warwick.